The Houston Astros will battle the Toronto Blue Jays in a Canada Day afternoon matchup on Monday. The Astros (42-41), who are in second place in the American League West, have won nine of 10. The Blue Jays (38-45), last in the AL East, have lost seven of 10.   

First pitch from Rogers Center in Toronto is set for 3:07 p.m. ET. Houston is the -146 money line favorite (risk $146 to win $100) in the latest Astros vs. Blue Jays odds, while the Blue Jays are a +123 underdog. The over/under for total runs scored is 8.5 and Houston is -1.5 (+115) on the run line in the latest baseball odds. Before you make any Astros vs. Blue Jays picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 14 of the 2024 MLB season 42-31 (+248) on all-top rated MLB picks this season. Dating back to last season, it is on a 21-8 roll on top-rated run-line picks (+869). Anybody following has seen STRONG returns!

The model knows second baseman Jose Altuve has been red hot of late. He has seven multi-hit games over the past 10, including a 3-for-5 performance with two doubles, two RBI and two runs scored in a 14-11 win over Baltimore on June 21. In a four-game stretch last week, he had two hits in each game, going 8-for-19 (.421) with two homers and four RBI from June 23 through Friday. Altuve is hitting .304 on the season with 13 homers, 37 RBI and 50 runs scored.

The model also knows first baseman Vladimir Guerrero Jr. has been among Toronto's top hitters. In 83 games this season, he is hitting .297 with 17 doubles, 13 homers, 50 RBI and 40 runs scored. He has hit in four consecutive games, including a 3-for-5 effort with a double, home run and six RBI in Saturday's 9-3 win over the New York Yankees. In the four-game series with New York, Guerrero was 8-for-17 (.471) with two doubles, three homers and 10 RBI.

The model has simulated Astros vs. Blue Jays 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, predicting a combined 8.9 runs, and it also says one side of the money line has ALL the value!

Who wins Astros vs. Blue Jays, and which side of the spread has ALL the value? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 42-31 roll on top-rated run-line MLB picks!